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పండుగ నాడు పడవ మునిగి 100మంది మృతి - టైగ్రిస్ నది
ఇరాక్ కుర్దీష్ కొత్త ఏడాది వేడుకల్లో తీవ్ర విషాదం చోటుచేసుకుంది. వేడుకల్లో పాల్గొనేందుకు వెళ్తోన్న పడవ ప్రమాదవశాత్తు టైగ్రిస్ నదిలో మునిగిపోయింది. ఈ ప్రమాదంలో 100 మందికిపైగా మృతి చెందారని అధికారులు తెలిపారు.
ఇరాక్లో పడవ ప్రమాaదం-71 మంది మృతి
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Published : Mar 22, 2019, 7:12 AM IST
| Updated : Mar 22, 2019, 7:49 AM IST
ఇరాక్లో పడవ ప్రమాదం-71 మంది మృతి ఇరాక్ నూతన సంవత్సర వేడుకల్లో తీవ్ర విషాదం చోటుచేసుకుంది. టైగ్రిస్ నదిలో జరిగిన ఘోరపడవ ప్రమాదంలో 100మందికి పైగాచనిపోయారు. మృతుల్లో మహిళలు, చిన్నారులే ఎక్కువగా ఉన్నట్లు ఇరాక్ అధికారవర్గాలు తెలిపాయి. కుర్దీష్ కొత్త సంవత్సరాన్ని పురస్కరించుకొని నౌరోజ్ వేడుకలు నిర్వహించారు. సంబరాల్లో పాల్గొనేందుకు పడవపై వెళ్తోన్న ప్రజలు మోసుల్ నగరానికి సమీపంలో ప్రమాదవశాత్తు నదిలో మునిగి చనిపోయారు.
పరిమితికి మించి పడవలో ప్రయాణించటమే ప్రమాదానికి కారణమని అధికారులు ప్రాథమికంగా గుర్తించారు. 19మంది చిన్నారులు సహా 55 మందిని రక్షించారు. ఆ ప్రాంతంలో ఎక్కువ పడవలు లేకపోవటం వల్ల మిగతా బాధితులను కాపాడలేకపోయినట్లు అధికారులు చెప్పారు.
ఇరాక్లో పడవ ప్రమాదం-71 మంది మృతి ఇరాక్ నూతన సంవత్సర వేడుకల్లో తీవ్ర విషాదం చోటుచేసుకుంది. టైగ్రిస్ నదిలో జరిగిన ఘోరపడవ ప్రమాదంలో 100మందికి పైగాచనిపోయారు. మృతుల్లో మహిళలు, చిన్నారులే ఎక్కువగా ఉన్నట్లు ఇరాక్ అధికారవర్గాలు తెలిపాయి. కుర్దీష్ కొత్త సంవత్సరాన్ని పురస్కరించుకొని నౌరోజ్ వేడుకలు నిర్వహించారు. సంబరాల్లో పాల్గొనేందుకు పడవపై వెళ్తోన్న ప్రజలు మోసుల్ నగరానికి సమీపంలో ప్రమాదవశాత్తు నదిలో మునిగి చనిపోయారు.
పరిమితికి మించి పడవలో ప్రయాణించటమే ప్రమాదానికి కారణమని అధికారులు ప్రాథమికంగా గుర్తించారు. 19మంది చిన్నారులు సహా 55 మందిని రక్షించారు. ఆ ప్రాంతంలో ఎక్కువ పడవలు లేకపోవటం వల్ల మిగతా బాధితులను కాపాడలేకపోయినట్లు అధికారులు చెప్పారు.
US PRESERVING FERTILITY
SOURCE: ASSOCIATED PRESS/PHOTO: COPYRIGHT OREGON NATIONAL PRIMATE RESEARCH CENTER AT OHSU/ VNR: COPYRIGHT OF OHSU (OREGON HEALTH AND SCIENCE UNIVERSITY)/ INTERVIEW FILMED BY UNIVERSITY OF PITTSBURGH, ANSWERS IN RESPONSE TO QUESTIONS FROM ASSOCIATED PRESS
RESTRICTIONS: AP Clients Only
LENGTH: 5.36
SHOTLIST:
PHOTO: COPYRIGHT OREGON NATIONAL PRIMATE RESEARCH CENTER AT OHSU
Oregon, US - April 2017
1. Colour photograph showing female macaque Grady who's birth resulted from reimplanted tissue from testes
INTERVIEW FILMED BY UNIVERSITY OF PITTSBURGH, ANSWERS IN RESPONSE TO QUESTIONS FROM ASSOCIATED PRESS
Oregon, US - 20 March 2019
2. SOUNDBITE (English) Professor Kyle Orwig, University of Pittsburgh School of Medicine
"Well her name's Grady which stands for graft derived baby. She was born on April 16th of last year and now she is 11 months old and she plays and behaves just like every other monkey that was born the normal way."
VNR: COPYRIGHT OF OHSU (OREGON HEALTH AND SCIENCE UNIVERSITY)
Oregon, US March 4, 2019
3. Shows Grady in her room at the Oregon National Primate Research Center at OHSU.
VNR: COPYRIGHT UNIVERSITY OF PITTSBURGH
Pittsburgh, US - 24 February 2019
4. Various of researcher marking samples at the Magee-Women's Research Institute
5. Close of samples on tray
6. Various of liquid being poured into sample storage tank
7. Close of sample being touched with dry ice
8. Various of samples being prepared for freeze storage in tank
INTERVIEW FILMED BY UNIVERSITY OF PITTSBURGH, ANSWERS IN RESPONSE TO QUESTIONS FROM ASSOCIATED PRESS
Oregon, US - 20 March 2019
9. SOUNDBITE (English) Professor Kyle Orwig, University of Pittsburgh School of Medicine
"We used some of the sperm, that was freshly isolated to fertilize eggs and that worked, but we did not establish a pregnancy that time. So we froze the rest of the sperm and then some months later we came back, brought that sperm out and fertilized eggs and that time we were successful to establish a pregnancy and finally to produce a healthy baby."
VNR: COPYRIGHT UNIVERSITY OF PITTSBURGH
Pittsburgh, US - 24 February 2019
10. Various of researcher carrying out ICSI procedure at Magee-Women's Research Institute
ASSOCIATED PRESS- AP Clients Only
Archive : Tampa, Florida, US - 10 February, 2011
11. Wide of Christine Hanlon in background with her son Dylan when he was being treated for cancer
12. Close of Dylan's face
13. Mid of Christine Hanlon, zooms out to Dylan
14. Mid of Hanlon picking up her research files
15. Wide of Dylan Hanlon walking with his feeding tube
ASSOCIATED PRESS - SKYPE INTERVIEW
Tampa, Florida, US - 20 March 2019
16. SOUNDBITE (English) Christine Hanlon, son has frozen tissue from testes
"I think it's great. I am very excited to hear that news and I'm very hopeful that these children are able to have an opportunity with this procedure going forward, that they may be able to you know survive whatever journey they're on and and have as close to a normal life going forward if they choose to do that and start their own family. I think it's wonderful."
ASSOCIATED PRESS - AP Clients Only
Archive : Pittsburgh, US - 23 February, 2011
17. Close of Dr. Orwig's hands looking at tissue on a slide
18. Close of Dr. Orwig putting slide under microscope
19. Mid of Dr Orwig looking through microscope
20. Mid of Orwig walking through lab
21. Various of researcher working in lab
ASSOCIATED PRESS - SKYPE INTERVIEW
Tampa, Florida, US - 20 March 2019
22. SOUNDBITE (English) Christine Hanlon, son has frozen tissue from testes
"For the ones who do make it, it's you know it's like they're already being robbed from their childhood. Life is never the same. The family's life is never the same.
ASSOCIATED PRESS- AP Clients Only
Archive : Tampa, Florida, US - 10 February, 2011
23. Various of Dylan Hanlon at the age of nine with his feeding tube
ASSOCIATED PRESS - SKYPE INTERVIEW
Tampa, Florida, US - 20 March 2019
24. SOUNDBITE (English) Christine Hanlon, son has frozen tissue from testes
"I was trying to be positive, optimistic, hopeful that things were going to be fine. And that he, it was then gonna to be my job to try and make him have the most normal life after that, that I could,"
VNR: COPYRIGHT OF OHSU (OREGON HEALTH AND SCIENCE UNIVERSITY)
Oregon, US March 4, 2019
25. Shows Grady in her room at the Oregon National Primate Research Center at OHSU with another monkey
ASSOCIATED PRESS - AP Clients Only
Maryland, US - 20 March 2019
26. SOUNDBITE (English) Susan Taymans, program director for fertility preservation, NIH (National Institutes of Health)
"Children with cancer, the treatments that they undergo, the radiation and the chemo and about a third of the cases will make them infertile when they reach adulthood and that's a big loss to somebody. Of course their survival is the primary concern, but after that in adulthood their quality of life issues and I think fertility is a really big one of those and so it's an important consideration before a child starts their treatment, to think about the ramifications for their future fertility and how you can protect and preserve that."
ASSOCIATED PRESS - AP Clients Only
Archive : Pittsburgh, US - 23 February, 2011
27. Various of researcher opening freezing tank and inserting samples
INTERVIEW FILMED BY UNIVERSITY OF PITTSBURGH, ANSWERS IN RESPONSE TO QUESTIONS FROM ASSOCIATED PRESS
Oregon, US - 20 March 2019
28. SOUNDBITE (English) Professor Kyle Orwig, University of Pittsburgh School of Medicine
"I feel that this was one of the last steps on the road to the human clinics so I believe that testicular tissue grafting as well as some other technologies may be available on a human clinic within the next two to five years."
VNR: COPYRIGHT OF OHSU (OREGON HEALTH AND SCIENCE UNIVERSITY)
Oregon, US March 4, 2019
29. Shows Grady in her room at the Oregon National Primate Research Center at OHSU with another monkey
LEAD IN:
Scientists say an experiment resulting in the birth of a baby monkey proves the success of a technology which could help young boys with cancer.
Gruelling treatments can damage fertility, destroying hopes of a future family, currently men can freeze sperm, but boys who haven't reached puberty don't have that option.
STORYLINE:
Meet Grady, the young macaque whose birth may signal a step change in fertility treatment available to young cancer patients.
According to scientists at the University of Pittsburgh her birth shows it may be possible to produce a baby monkey from frozen testicular tissue.
It's an achievement lead scientist Professor Kyle Orwig and his team have worked years for.
"Well her name's Grady which stands for graft derived baby. She was born on April 16th of last year and now she is 11 months old and she plays and behaves just like every other monkey that was born the normal way," says Orwig.
Grady's father was a macaque whose testicular tissue was removed before he reached maturity. As with us human primates there is no sperm at this stage.
Boys are born with stem cells inside little tubes in the testes, cells that start producing sperm after puberty.
Orwig's goal is to keep sperm-producing stem cells safe from cancer treatment by freezing biopsy-sized pieces of testicular tissue.
Sperm production is kickstarted by hormonal changes during puberty activating an increase in testosterone.
This tells stem cells in the testes to start producing sperm.
Treatments like chemotherapy and radiation can damage the stem cells before they start production leading to permanent infertility
Grady's father had the thawed testicular tissue was reimplanted under his skin.
Boosted by testosterone, the little pieces of tissue grew fatter. Months later, the researchers removed them and inside the tissue was sperm they could collect and freeze.
"We used some of the sperm, that was freshly isolated to fertilize eggs and that worked, but we did not establish a pregnancy that time. So we froze the rest of the sperm and then some months later we came back, brought that sperm out and fertilized eggs and that time we were successful to establish a pregnancy and finally to produce a healthy baby," says Orwig.
The recovered sperm was implanted into Grady's mother using a technique intracytoplasmic sperm injection known as ICSI.
This is an IVF procedure where an individual sperm injected directly into the egg.
Researchers say the success of one of the fresh embryos was confirmed by ultrasound in January 2018.
The University of Pittsburgh and a few other hospitals have been freezing young boys' immature testicular tissue ahead of cancer treatment on an experimental basis.
One of them was nine-year-old Dylan Hanlon whose tissue was banked back in 2011.
Dylan had Ewing's Sarcoma, a rare childhood cancer in his soft tissue and his doctors said he needed nine months of intensive chemotherapy.
The treatment was successful and on the 29th March this month Dylan will be eighteen.
At this stage neither he, nor his mother Christine Hanlon know whether he is fertile, or whether he will need to use his banked tissue in the future.
Hearing of the monkey's birth Hanlon says: "I think it's great. I am very excited to hear that news and I'm very hopeful that these children are able to have an opportunity with this procedure going forward, that they may be able to you know survive whatever journey they're on and and have as close to a normal life going forward if they choose to do that and start their own family. I think it's wonderful."
Hanlon says it''s important parents look to the future.
"For the ones who do make it, it's you know it's like they're already being robbed from their childhood. Life is never the same. The family's life is never the same," she says.
For Hanlon it's important she's done all she can to secure her son's future happiness.
"I was trying to be positive, optimistic, hopeful that things were going to be fine. And that he, it was then gonna to be my job to try and make him have the most normal life after that, that I could," says Hanlon.
The result of the study published in the journal Science is welcomed by Dr. Susan Taymens at America's Institute of Health.
She says: "Children with cancer, the treatments that they undergo, the radiation and the chemo and about a third of the cases will make them infertile when they reach adulthood and that's a big loss to somebody. Of course their survival is the primary concern, but after that in adulthood their quality of life issues and I think fertility is a really big one of those and so it's an important consideration before a child starts their treatment, to think about the ramifications for their future fertility and how you can protect and preserve that."
Girls are born with all the eggs they'll ever have but they're in an immature state before puberty.
Researchers have removed and frozen strips of ovaries harboring egg follicles from young women before cancer treatment.
They transplant the tissue back into the abdomen a few years later.
It's considered experimental even for young adults but some births have been reported, and now some hospitals bank ovarian tissue from girls, too.
Orwig believes his latest study is the proof of principal needed:
"I feel that this was one of the last steps on the road to the human clinics so I believe that testicular tissue grafting as well as some other technologies may be available on a human clinic within the next two to five years."
At Pittsburgh Orwig has frozen tissue from 200 patient's testes and banked the ovarian tissue of forty female patients.
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Last Updated : Mar 22, 2019, 7:49 AM IST
