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IIT Indore develops cost-effective drug for Leukemia

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Published : Mar 29, 2021, 7:31 AM IST

Updated : Mar 29, 2021, 9:46 AM IST

The Indian Institute of Technology Indore has developed new cost-effective drug asparaginase (MASPAR) using a protein engineering approach for the treatment of acute lymphoblastic leukaemia.

IIT Indore develops cost-effective drug for Leukemia
IIT Indore develops cost-effective drug for Leukemia

Indore (Madhya Pradesh): The Indian Institute of Technology (IIT) Indore has developed new cost-effective drug asparaginase (MASPAR) using a protein engineering approach for the treatment of acute lymphoblastic leukaemia (ALL).

The drug with no or fewer side effects has been developed after 12 years of research.

Leukaemia is a type of blood cancer and every year around 25000 new cases are found in India. The percentage of children among the patients is nearly one fourth.

READ: Former I-League winner Surojit Bose battling blood cancer

The repeated doses of asparaginase, which is currently used to treat all patients, can cause serious allergic reactions, hypersensitivity, and toxicity to the pancreas including many other organs.

In such a situation, this medicine will benefit the patients to a great extent. The medicine will also be of great use to the patients who recover and are again affected by the disease.

IIT-Indore in collaboration with advanced centres for cancer treatment, research and education, Tata Memorial Centers (ACTREC, TMC), Mumbai, and Mumbai-based bio pharmacy companies will soon start Phase I and Phase II clinical trials of the drug.

READ: Lymphoma Patients Highly Vulnerable To COVID-19

In the first phase, 25 to 30 people will be tested for drug safety, tolerance.

Professor Neelesh Jain, director (officiating), said that research has always been the primary work of institutes like IITs.

READ: Teenage cancer patient pens down book to inspire others

"Such developments in the field of human health lead to significant reductions in side effects and, most importantly, are essential to reducing treatment costs. The Institute strongly supports Phase I and II trials until a logical conclusion is reached,“ he added.

Indore (Madhya Pradesh): The Indian Institute of Technology (IIT) Indore has developed new cost-effective drug asparaginase (MASPAR) using a protein engineering approach for the treatment of acute lymphoblastic leukaemia (ALL).

The drug with no or fewer side effects has been developed after 12 years of research.

Leukaemia is a type of blood cancer and every year around 25000 new cases are found in India. The percentage of children among the patients is nearly one fourth.

READ: Former I-League winner Surojit Bose battling blood cancer

The repeated doses of asparaginase, which is currently used to treat all patients, can cause serious allergic reactions, hypersensitivity, and toxicity to the pancreas including many other organs.

In such a situation, this medicine will benefit the patients to a great extent. The medicine will also be of great use to the patients who recover and are again affected by the disease.

IIT-Indore in collaboration with advanced centres for cancer treatment, research and education, Tata Memorial Centers (ACTREC, TMC), Mumbai, and Mumbai-based bio pharmacy companies will soon start Phase I and Phase II clinical trials of the drug.

READ: Lymphoma Patients Highly Vulnerable To COVID-19

In the first phase, 25 to 30 people will be tested for drug safety, tolerance.

Professor Neelesh Jain, director (officiating), said that research has always been the primary work of institutes like IITs.

READ: Teenage cancer patient pens down book to inspire others

"Such developments in the field of human health lead to significant reductions in side effects and, most importantly, are essential to reducing treatment costs. The Institute strongly supports Phase I and II trials until a logical conclusion is reached,“ he added.

Last Updated : Mar 29, 2021, 9:46 AM IST
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