Bissonnette, now 29, pleaded guilty last March to six charges of first-degree murder and six of attempted murder. More than 50 people were at the Islamic Cultural Centre in January 2017 when he began shooting during evening prayers.
Bissonnette received a life sentence and can apply for parole after 40 years, but that doesn't mean he's likely to get parole.
The judge began his ruling on Friday by saying the day of the murders "will forever be written in blood in the history of this city, this province, this country."
Those who monitor extremist groups in Quebec described the university student as someone who took extreme nationalist positions at Laval University and on social media. He was a supporter of French far-right leader Marine Le Pen and U.S. President Donald Trump.
Quebec's previous premier previously acknowledged the province has its "demons" in terms of attitudes toward Muslims.
Canada is generally welcoming toward immigrants and all religions, but the French-speaking province of Quebec has had a long-simmering debate about race and religious accommodation.
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(With inputs from APTN)