New York:Russian second seed Daniil Medvedev further cemented his title credentials overcoming qualifier Botic van de Zandschulp of the Netherlands 6-3, 6-0, 4-6, 7-5 to reach his third consecutive US Open semifinal here.
Djokovic will next face 12th seed Canadian Auger-Aliassime, who made his first major semifinal at the US Open after Spanish giant-killer Carlos Alcaraz retired due to an injury trailing 6-3, 3-1.
The Russian, who captured his 200th career win in the first-round victory against Richard Gasquet of France, had not dropped a set before Tuesday.
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The world No. 2 played with confidence against van de Zandschulp, firing 36 winners and winning 83 per cent (54/65) of first-serve points as he raised his level in the fourth set to advance after two hours and 22 minutes.
"First two sets he was missing and I was controlling the game," Medevedev said. "But then he started missing less and hit with more power and played more aggressively. The break point he won he hit a forehand winner, so it became a lot tougher for me.
"I am happy with my game in the fourth set because on my first serve, I only lost two points and I always felt under pressure. Then at 6-5 he got a little bit tight, and I managed to do it without the tie-break, which is helpful," Medvedev told atptour.com.
Chasing his maiden Major title, Medvedev remains on course for a potential blockbuster final against world No. 1 Novak Djokovic, who is aiming to capture the Grand Slam at the US Open. The 25-year-old will first have to overcome a tricky test against either 12th seed Felix Auger-Aliassime in the last four.