Booster doses of current vaccines may not be enough, warns WHO

WHO's Technical Advisory Group on Covid-19 Vaccine Composition has said that although current vaccines provide a high level of protection against severe disease and death caused by Variants Of Concern (VOC), future vaccines that can prevent infection and transmission need to be developed.

Geneva (Switzerland): The World Health Organisation (WHO) has said that current Covid-19 vaccines may need to be updated if they are to provide continued protection against emerging variants, including Omicron.

WHO's Technical Advisory Group on Covid-19 Vaccine Composition (TAG-CO-VAC), a group of 18 experts, on Tuesday said that although current vaccines provide a high level of protection against severe disease and death caused by Variants Of Concern (VOC), future vaccines that can prevent infection and transmission need to be developed.

"A vaccination strategy based on repeated booster doses of the original vaccine composition is unlikely to be appropriate or sustainable," the WHO Technical Advisory Group said in a statement. It said preliminary data indicated the existing vaccines were less effective at preventing symptomatic Covid disease in people who have contracted the new Omicron variant, currently spreading like wildfire around the world.s.

"In the meantime, the composition of current Covid-19 vaccines may need to be updated in order to protect against the evolution of the virus. Such updates need to be based on strains that are genetically and antigenically close to the circulating variants. They should also elicit broad, strong, and long-lasting responses in order to reduce the need for successive booster doses," WHO added.

The experts have encouraged Covid-19 vaccine manufacturers to provide data on the performance of current and Omicron-specific vaccines, to help decide when changes to vaccine composition may be required. Regarding the current Omicron variant, the experts emphasised the importance of wider global access to the current Covid-19 vaccine

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